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Literature summary extracted from
- myo-inositol monophosphatase: a challenging target for mood stabilising drugs (2007), Mini Rev. Med. Chem., 7, 107-113.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.25 | (1R,2R,4R,6R)-2,4-dihydroxy-6-[4-(2-hydroxyphenyl)butoxy]cyclohexyl phosphate | - |
Homo sapiens |  |
| 3.1.3.25 | (1S,2R,4S,6R)-6-(butylamino)cyclohexane-1,2,4-triol | - |
Homo sapiens | |
| 3.1.3.25 | (phenylmethanediyl)bis(phosphonic acid) | - |
Homo sapiens | |
| 3.1.3.25 | 1-(4-hydroxyphenyloxy)ethane-1,1-bisphosphonic acid | - |
Homo sapiens | |
| 3.1.3.25 | 2,3,7-trihydroxycyclohepta-2,4,6-trien-1-one | - |
Homo sapiens | |
| 3.1.3.25 | Li+ | - |
Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.25 | Mg2+ | cofactor requirement for 3 Mg2+ ions | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.25 | 60000 | - |
SDS-PAGE | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.25 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.25 | alpha-D-galactose 1-phosphate + H2O | - |
Homo sapiens | alpha-D-galactose + phosphate | - |
? | |
| 3.1.3.25 | D-erythrose 4-phosphate + H2O | - |
Homo sapiens | D-erythrose + phosphate | - |
? | |
| 3.1.3.25 | D-fructose 1,6-bisphosphate + H2O | - |
Homo sapiens | D-fructose 6-phosphate + phosphate | - |
? | |
| 3.1.3.25 | D-fructose 1-phosphate + H2O | - |
Homo sapiens | D-fructose + phosphate | - |
? | |
| 3.1.3.25 | D-fructose 6-phosphate + H2O | - |
Homo sapiens | D-fructose + phosphate | - |
? | |
| 3.1.3.25 | D-glucose 6-phosphate + H2O | - |
Homo sapiens | D-glucose + phosphate | - |
? | |
| 3.1.3.25 | D-myo-inositol 1-phosphate + H2O | - |
Homo sapiens | D-myo-inositol + phosphate | - |
? | |
| 3.1.3.25 | D-ribose 5-phosphate + H2O | - |
Homo sapiens | D-ribose + phosphate | - |
? | |
| 3.1.3.25 | D-xylose 5-phosphate + H2O | - |
Homo sapiens | D-xylose + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.25 | homodimer | - |
Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.3.25 | IMPase | - |
Homo sapiens |
| 3.1.3.25 | myo-inositol monophosphatase | - |
Homo sapiens |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.25 | 0.3 | - |
(1S,2R,4S,6R)-6-(butylamino)cyclohexane-1,2,4-triol | - |
Homo sapiens | |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.25 | 0.00007 | - |
- |
Homo sapiens | (1R,2R,4R,6R)-2,4-dihydroxy-6-[4-(2-hydroxyphenyl)butoxy]cyclohexyl phosphate | |
| 3.1.3.25 | 0.0002 | - |
- |
Homo sapiens | 1-(4-hydroxyphenyloxy)ethane-1,1-bisphosphonic acid | |
| 3.1.3.25 | 0.0002 | - |
- |
Homo sapiens | (phenylmethanediyl)bis(phosphonic acid) | |
| 3.1.3.25 | 0.0008 | - |
- |
Homo sapiens | 2,3,7-trihydroxycyclohepta-2,4,6-trien-1-one | |
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