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Literature summary extracted from

  • Vanisree, A.J.; Shyamaladevi, C.S.
    The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells - in vitro (2006), Life Sci., 79, 654-659.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 N-acetylcysteine decreases enzyme activity in lung carcinoma NCI-H82 cells and reduces the cell viability, overview Homo sapiens
4.1.1.17 vitamin C decreases enzyme activity in lung carcinoma NCI-H82 cells and reduces the cell viability, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.17 L-ornithine Homo sapiens
-
 putrescine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.17 lung
-
 Homo sapiens
-
4.1.1.17 lung carcinoma cell
-
 Homo sapiens
-
4.1.1.17 NCI-H82 cell lung carcinoma cell line Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-ornithine
-
 Homo sapiens putrescine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.17 ODC
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.17 6.8
-
 assay at Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.17 pyridoxal 5'-phosphate
-
 Homo sapiens