Literature summary extracted from

Tang, S.C.; Leung, J.C.; Chan, L.Y.; Eddy, A.A.; Lai, K.N.
Angiotensin converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy (2008), Kidney Int., 73, 288-299.

Application

EC Number	Application	Comment	Organism
3.4.15.1	medicine	angiotensin-converting enzyme inhibition confers renoprotection in adriamycin nephropathy by reducing intrarenal angiotensin II and augmenting expression of N-acetylseryl-aspartyl-lysyl-proline that together attenuate signaling of mitogen-activated protein kinase and its downstream proinflammatory and fibrinogenic properties	Mus musculus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.15.1	captopril	angiotensin-converting enzyme inhibition confers renoprotection in adriamycin nephropathy by reducing intrarenal angiotensin II and augmenting expression of N-acetylseryl-aspartyl-lysyl-proline that together attenuate signaling of mitogen-activated protein kinase and its downstream proinflammatory and fibrinogenic properties	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.15.1	Mus musculus	-	-	-

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Release 2023.1 (January 2023)