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Literature summary extracted from

  • Valle, L.D.; Toffolo, V.; Nardi, A.; Fiore, C.; Bernante, P.; Di Liddo, R.; Parnigotto, P.P.; Colombo, L.
    Tissue-specific transcriptional initiation and activity of steroid sulfatase complementing dehydroepiandrosterone sulfate uptake and intracrine steroid activations in human adipose tissue (2006), J. Endocrinol., 190, 129-139.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.6.2 64000
-
 x * 64000, SDS-PAGE of enzymes from placenta and adipose tissue Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.2 dehydroepiandrosterone 3-sulfate + H2O Homo sapiens in adipose tissue, further concersion to bioactive androgens and estrogens dehydroepiandrosterone + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.2 Homo sapiens P08842
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.2 adipose tissue transcription is regulated by two promoters which differ from the prevalent placental one. Specific activity of adipose tissue enzyme is about 50-100 times lower than by placenta enzyme Homo sapiens
-
3.1.6.2 placenta specific activity of adipose tissue enzyme is about 50-100 times lower than by placenta enzyme Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.2 dehydroepiandrosterone 3-sulfate + H2O
-
 Homo sapiens dehydroepiandrosterone + sulfate
-
 ?
3.1.6.2 dehydroepiandrosterone 3-sulfate + H2O in adipose tissue, further concersion to bioactive androgens and estrogens Homo sapiens dehydroepiandrosterone + sulfate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.6.2 ? x * 64000, SDS-PAGE of enzymes from placenta and adipose tissue Homo sapiens