Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Brough, D.; Rothwell, N.J.
    Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death (2007), J. Cell Sci., 120, 772-781.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.36 cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.36 pre-interleukin-1beta + H2O Mus musculus caspase-1-dependent processing of pro-interleukin-1beta can occur in the cytosol following activation of P2X7-receptor. Structural changes preceding cell death, occurring after caspase-1 activation, promote the cellular release of interleukin-1beta interleukin-1beta + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.36 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.36 macrophage
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.36 pre-interleukin-1beta + H2O
-
 Mus musculus interleukin-1beta + ?
-
 ?
3.4.22.36 pre-interleukin-1beta + H2O caspase-1-dependent processing of pro-interleukin-1beta can occur in the cytosol following activation of P2X7-receptor. Structural changes preceding cell death, occurring after caspase-1 activation, promote the cellular release of interleukin-1beta Mus musculus interleukin-1beta + ?
-
 ?