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Literature summary extracted from

  • Zhan, M.; Jin, B.; Chen, S.; Reecy, J.M.; Li, Y.
    TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis (2007), J. Cell Sci., 120, 692-701.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.86 TAPI selective inhibitor Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.86 17000
-
 mature enzyme, SDS-PAGE Mus musculus
3.4.24.86 26000
-
 pro-enzyme, SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.86 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.86 C2C12 cell
-
 Mus musculus
-
3.4.24.86 myoblast
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.86 p75 tumour necrosis factor receptor + H2O
-
 Mus musculus ?
-
 ?
3.4.24.86 proTNF-alpha + H2O
-
 Mus musculus soluble TNF-alpha
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.86 ADAM17
-
 Mus musculus
3.4.24.86 TACE
-
 Mus musculus
3.4.24.86 TNF-alpha converting enzyme
-
 Mus musculus