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Literature summary extracted from

  • Emami, N.; Diamandis, E.P.
    Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin (2008), J. Biol. Chem., 283, 3031-3041.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B45 Homo sapiens Q9P0G3
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.B45 seminal plasma
-
 Homo sapiens
-
3.4.21.B45 skin
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B45 Ala-Thr-Pro-Lys-Ile-Phe-Asn + H2O 19% cleavage after 1 h incubation Homo sapiens Ala-Thr-Pro-Lys + Ile-Phe-Asn
-
 ?
3.4.21.B45 D-Val-Leu-Lys-thiobenzyl ester + H2O low activity Homo sapiens D-Val-Leu-Lys + thiobenzyl alcohol
-
 ?
3.4.21.B45 L-Gln-Gly-Asp-Lys-Ile-Ile-Asp + H2O 41% cleavage after 1 h incubation Homo sapiens L-Gln-Gly-Asp-Lys + Ile-Ile-Asp
-
 ?
3.4.21.B45 L-Glu-Thr-Arg-Ile-Ile-Lys + H2O 55% cleavage after 1 h incubation Homo sapiens L-Glu-Thr-Arg + Ile-Ile-Lys
-
 ?
3.4.21.B45 L-Ile-Gln-Ser-Arg-Ile-Val-Gly + H2O 97% cleavage after 1 h incubation Homo sapiens L-Ile-Gln-Ser-Arg + Ile-Val-Gly
-
 ?
3.4.21.B45 L-Ile-Leu-Ser-Arg-Ile-Val-Gly + H2O 87% cleavage after 1 h incubation Homo sapiens L-Ile-Leu-Ser-Arg + Ile-Val-Gly
-
 ?
3.4.21.B45 L-Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens L-Pro-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
3.4.21.B45 L-Ser-Ser-Ser-Arg-Ile-Ile-Asn + H2O 57% cleavage after 1 h incubation Homo sapiens L-Ser-Ser-Ser-Arg + Ile-Ile-Asn
-
 ?
3.4.21.B45 additional information does not cleave L-Glu-Ser-Ser-Lys-Val-Leu-Asn, L-Ser-Cys-Ser-Gln-Ile-Ile-Asn, L-Glu-Gln-Asn-Lys-Leu-Val-His, L-Gln-Glu-Asp-Lys-Val-Leu-Gly, L-Asp-Thr-Arg-Ala-Ile-Gly, L-Asn-Asp-Thr-Arg-Leu-Asp-Pro, L-Asp-Glu-Asn-Lys-Ile-Ile-Gly, and L-Asp-Gly-Asp-Lys-Leu-Leu-Glu Homo sapiens ?
-
 ?
3.4.21.B45 pro-KLK11 + H2O
-
 Homo sapiens KLK11 + ?
-
 ?
3.4.21.B45 pro-KLK3 + H2O KLK3 is activated by cleavage after arginine at position 7 Homo sapiens KLK3 + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B45 kallikrein-related peptidase 14
-
 Homo sapiens
3.4.21.B45 KLK14
-
 Homo sapiens