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Literature summary extracted from

  • Chon, S.H.; Zhou, Y.X.; Dixon, J.L.; Storch, J.
    Intestinal monoacylglycerol metabolism: developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase (2007), J. Biol. Chem., 282, 33346-33357.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.23 additional information high fat feeding induces the enzyme in the intestine, but starvation does not have an effect on the enzyme activity Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.23 quantitative RT-PCR for analysis of intestinal MGL mRNA expression Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.23 additional information Homo sapiens developmental and nutritional regulation of the enzyme in the intestine, overview ?
-
 ?
3.1.1.23 additional information Mus musculus tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview ?
-
 ?
3.1.1.23 additional information Mus musculus C57BL/6 tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.23 Homo sapiens
-
-
-
3.1.1.23 Mus musculus
-
 C57BL/6 mice
-
3.1.1.23 Mus musculus C57BL/6
-
 C57BL/6 mice
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.23 adipose tissue
-
 Mus musculus
-
3.1.1.23 Caco-2 cell
-
 Homo sapiens
-
3.1.1.23 enterocyte
-
 Homo sapiens
-
3.1.1.23 intestine
-
 Homo sapiens
-
3.1.1.23 liver liver MGL mRNA, protein and activity all increased 5-10-fold during development Mus musculus
-
3.1.1.23 small intestine mucosa, post-transcriptional regulation of expression, the enzyme expression is also developmentally regulated, quantitative RT-PCR analysis, overview Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.23 additional information developmental and nutritional regulation of the enzyme in the intestine, overview Homo sapiens ?
-
 ?
3.1.1.23 additional information tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview Mus musculus ?
-
 ?
3.1.1.23 additional information tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview Mus musculus C57BL/6 ?
-
 ?
3.1.1.23 sn-2-monoolein + H2O
-
 Mus musculus glycerol + oleic acid
-
 ?
3.1.1.23 sn-2-monoolein + H2O
-
 Homo sapiens glycerol + oleic acid
-
 ?
3.1.1.23 sn-2-monoolein + H2O
-
 Mus musculus C57BL/6 glycerol + oleic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.23 MGL
-
 Mus musculus
3.1.1.23 MGL
-
 Homo sapiens
3.1.1.23 monoacylglycerol lipase
-
 Mus musculus
3.1.1.23 monoacylglycerol lipase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.23 23
-
 assay at Mus musculus
3.1.1.23 23
-
 assay at Homo sapiens