Literature summary extracted from

Soejima, K.; Nakamura, H.; Hirashima, M.; Morikawa, W.; Nozaki, C.; Nakagaki, T.
Analysis on the molecular species and concentration of circulating ADAMTS13 in blood (2006), J. Biochem., 139, 147-154.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.4.24.87	expressed in HEK-293 cells	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.87	W688X6-1	the monoclonal antibody W688X6-1 shows dose-dependent inhibitory activity toward ADAMTS13-mediated hydrolysis	Homo sapiens
3.4.24.87	WH2-22-1A	the monoclonal antibody WH2-22-1A shows dose-dependent inhibitory activity toward ADAMTS13-mediated hydrolysis	Homo sapiens

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.4.24.87	150000	-	full-length form, SDS-PAGE	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.24.87	von Willebrand factor + H2O	Homo sapiens	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.87	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.24.87	HiLoad Superdex 200 gel filtration	Homo sapiens

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.87	blood plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.87	fluorescence resonance energy transfer substrate-von Willebrand factor 73 + H2O	-	Homo sapiens	?	-	?
3.4.24.87	von Willebrand factor + H2O	-	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.24.87	ADAMTS13	-	Homo sapiens
3.4.24.87	von Willebrand factor-cleaving protease	-	Homo sapiens
3.4.24.87	VWF cleaving protease	-	Homo sapiens
3.4.24.87	VWF-CP	-	Homo sapiens

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Release 2023.1 (January 2023)