EC Number | Cloned (Comment) | Organism |
---|---|---|
4.3.3.2 | - |
Catharanthus roseus |
4.3.3.2 | for expression in Escherichia coli | Rauvolfia serpentina |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
4.3.3.2 | cocrystallized with inhibitor 6, the complete data are collected to 3.0 A resolution | Rauvolfia serpentina |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.3.3.2 | 3-[(tert-butoxycarbonyl)amino]propyl (3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-(2-oxoethyl)-3,4-dihydro-2H-pyran-5-carboxylate | - |
Catharanthus roseus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.3.2 | 3-alpha(S)-strictosidine + H2O | Catharanthus roseus | - |
tryptamine + secologanin | - |
? | |
4.3.3.2 | 3-alpha(S)-strictosidine + H2O | Rauvolfia serpentina | - |
tryptamine + secologanin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.3.3.2 | Catharanthus roseus | - |
- |
- |
4.3.3.2 | Rauvolfia serpentina | P68175 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.3.3.2 | - |
Catharanthus roseus |
4.3.3.2 | - |
Rauvolfia serpentina |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.3.2 | 3-alpha(S)-strictosidine + H2O | - |
Catharanthus roseus | tryptamine + secologanin | - |
? | |
4.3.3.2 | 3-alpha(S)-strictosidine + H2O | - |
Rauvolfia serpentina | tryptamine + secologanin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.3.3.2 | strictosidine synthase | - |
Catharanthus roseus |
4.3.3.2 | strictosidine synthase | - |
Rauvolfia serpentina |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.3.3.2 | 30 | - |
activity assay | Catharanthus roseus |
4.3.3.2 | 30 | - |
activity assay | Rauvolfia serpentina |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.3.3.2 | 7 | - |
activity assay | Catharanthus roseus |
4.3.3.2 | 7 | - |
activity assay | Rauvolfia serpentina |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
4.3.3.2 | 0.000003 | - |
- |
Catharanthus roseus | 3-[(tert-butoxycarbonyl)amino]propyl (3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-(2-oxoethyl)-3,4-dihydro-2H-pyran-5-carboxylate |