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Literature summary extracted from

  • Loh, J.T.; Cover, T.L.
    Requirement of histidine kinases HP0165 and HP1364 for acid resistance in Helicobacter pylori (2006), Infect. Immun., 74, 3052-3059.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.7.13.3 additional information intact HP0165 and HP1364 histidine kinases are required for acid resistance in Helicobacter pylori Helicobacter pylori

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.13.3 into vector pGEM-T, then cloned genes disrupted in HP0244, HP1364, and HP0165 sequences. The resulting plasmids, which are unable to replicate in Helicobacter pylori, introduced into Helicobacter pylori J99 Helicobacter pylori

Protein Variants

EC Number Protein Variants Comment Organism
2.7.13.3 additional information growth of HP0244 mutant strain is similar to the growth of the wild-type strain, null mutations in either HP0165 or HP1364 histidine kinases are impaired in their ability to grow at pH 5.0, acid-responsive gene transcription is altered in the HP0165 and HP1364 null mutant strains compared to the parental wild-type strain, growth of complemented mutant strains is similar to that of the wild-type strain Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
2.7.13.3 Helicobacter pylori
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.7.13.3 histidine kinase
-
Helicobacter pylori
2.7.13.3 HP0165
-
Helicobacter pylori
2.7.13.3 HP1364
-
Helicobacter pylori

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.13.3 5 7
-
Helicobacter pylori