EC Number | Application | Comment | Organism |
---|---|---|---|
3.1.1.13 | medicine | lowering of cholesterol levels in plasma low-density lipoprotein by cardiovascular drugs such as lovastatin, simvastatin, amlodipine, besylate, nifedipine, and hydralazine hydrochloride may result from inhibition of cholesterol esterase | Bos taurus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.13 | amlodipine | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus | |
3.1.1.13 | besylate | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus | |
3.1.1.13 | hydralazine hydrochloride | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus | |
3.1.1.13 | lovastatin | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus | |
3.1.1.13 | additional information | pKi values of cardiovascular drug inhibitors such as lovastatin, simvastatin, amlodipine, besylate, nifedipine, and hydralazine hydrochloride correlate with their molecular weight | Bos taurus | |
3.1.1.13 | nifedipine | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus | |
3.1.1.13 | simvastatin | mixed-type, study on kinetics in presence of Triton X-100 or taurocholate | Bos taurus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.13 | Bos taurus | - |
- |
- |