EC Number | Cloned (Comment) | Organism |
---|---|---|
4.6.1.2 | full-length genomic gcy gene sequence fused to the GFP gene and injected into wild-type animals | Caenorhabditis elegans |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.6.1.2 | additional information | double mutants for gcy genes show defects in thermotaxis, triple mutants for the gcy genes show severe defects in thermotaxis but respond normally to odorants and NaCl, abnormal phenotype of the gcy triple mutants can be rescued by expression of any one of the three GCY proteins, gcy-8, gcy-18, and gcy-23. In the AFD neurons no defects in thermotaxis behaviors in gcy single mutants | Caenorhabditis elegans |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.2 | Caenorhabditis elegans | - |
variety Bristol (N2) | - |
4.6.1.2 | Caenorhabditis elegans | Q9GYQ4 | variety Bristol (N2) | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.6.1.2 | - |
Caenorhabditis elegans |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.6.1.2 | neuron | expressed specifically in the AFD thermosensory neurons | Caenorhabditis elegans | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.2 | GTP | - |
Caenorhabditis elegans | 3',5'-cyclic GMP + diphosphate | regulation of intracellular cGMP concentration is essential for normal thermotaxis | ? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.2 | gcy-18 | - |
Caenorhabditis elegans |
4.6.1.2 | gcy-23 | - |
Caenorhabditis elegans |
4.6.1.2 | gcy-8 | - |
Caenorhabditis elegans |
4.6.1.2 | receptor-type guanylyl cyclase | - |
Caenorhabditis elegans |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.6.1.2 | 15 | 25 | - |
Caenorhabditis elegans |