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Literature summary extracted from

  • Fujimori, K.; Inui, T.; Uodome, N.; Kadoyama, K.; Aritake, K.; Urade, Y.
    Zebrafish and chicken lipocalin-type prostaglandin D synthase homologues: Conservation of mammalian gene structure and binding ability for lipophilic molecules, and difference in expression profile and enzyme activity (2006), Gene, 375, 14-25.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.2
-
 Mus musculus
5.3.99.2
-
 Danio rerio
5.3.99.2
-
 Gallus gallus

Protein Variants

EC Number Protein Variants Comment Organism
5.3.99.2 G59C C59 is an essential residue for enzyme activity in mammals. Mutant G59C does not show enzymic activity Danio rerio
5.3.99.2 additional information chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184, shows weak enzymic activity Mus musculus
5.3.99.2 additional information chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184, shows weak enzymic activity Danio rerio

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.99.2 28600
-
 x * 28600, calculated Danio rerio

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.2 Danio rerio Q8QGV4 homologue of lipocalin-type prostaglandin synthase, no enzymic activity
-
5.3.99.2 Gallus gallus Q8QFM7 homologue of lipocalin-type prostaglandin synthase, weak enzymic activity
-
5.3.99.2 Mus musculus
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.3.99.2 11.7
-
 pH 8.0, 25°C Gallus gallus
5.3.99.2 14.9
-
 chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184 Mus musculus
5.3.99.2 14.9
-
 chimeric protein construct carrying the mouse amino-terminal portion from D25 to L84, and zebrafish carboxyl-terminal portion from K79 to A184 Danio rerio
5.3.99.2 434
-
 wild-type, pH 8.0, 25°C Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.2 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
-
 Mus musculus (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
-
 ?
5.3.99.2 (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
-
 Gallus gallus (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.99.2 ? x * 28600, calculated Danio rerio