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Literature summary extracted from

  • Landete, J.M.; Pardo, I.; Ferrer, S.
    Histamine, histidine, and growth-phase mediated regulation of the histidine decarboxylase gene in lactic acid bacteria isolated from wine (2006), FEMS Microbiol. Lett., 260, 84-90.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.22 additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Oenococcus oeni
4.1.1.22 additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Lentilactobacillus hilgardii
4.1.1.22 additional information L-histidine induces the expression of the histidine decarboxylase gene hdc Pediococcus parvulus
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Oenococcus oeni
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Lentilactobacillus hilgardii
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Pediococcus parvulus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.22 additional information histamine causes a decrease in the expression of gene hdc Lentilactobacillus hilgardii
4.1.1.22 additional information histamine causes a decrease in the expression of gene hdc Oenococcus oeni
4.1.1.22 additional information histamine causes a decrease in the expression of gene hdc Pediococcus parvulus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.22 L-histidine Oenococcus oeni expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?
4.1.1.22 L-histidine Lentilactobacillus hilgardii expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?
4.1.1.22 L-histidine Pediococcus parvulus expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?
4.1.1.22 L-histidine Pediococcus parvulus P270 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?
4.1.1.22 L-histidine Lentilactobacillus hilgardii 464 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?
4.1.1.22 L-histidine Oenococcus oeni 4042 expression of hdc is also mediated by the bacterial growth phase, overview histamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Lentilactobacillus hilgardii
-
 isolated from wine, gene hdc
-
4.1.1.22 Lentilactobacillus hilgardii 464
-
 isolated from wine, gene hdc
-
4.1.1.22 Oenococcus oeni
-
 isolated from wine, gene hdc
-
4.1.1.22 Oenococcus oeni 4042
-
 isolated from wine, gene hdc
-
4.1.1.22 Pediococcus parvulus
-
 isolated from wine, gene hdc
-
4.1.1.22 Pediococcus parvulus P270
-
 isolated from wine, gene hdc
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.22 additional information
-
-
 Lentilactobacillus hilgardii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Oenococcus oeni histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Lentilactobacillus hilgardii histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Pediococcus parvulus histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Oenococcus oeni histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Lentilactobacillus hilgardii histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Pediococcus parvulus histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Pediococcus parvulus P270 histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Pediococcus parvulus P270 histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Lentilactobacillus hilgardii 464 histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Lentilactobacillus hilgardii 464 histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Oenococcus oeni 4042 histamine + CO2
-
 ?
4.1.1.22 L-histidine expression of hdc is also mediated by the bacterial growth phase, overview Oenococcus oeni 4042 histamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.22 HDC
-
 Oenococcus oeni
4.1.1.22 HDC
-
 Lentilactobacillus hilgardii
4.1.1.22 HDC
-
 Pediococcus parvulus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.22 37
-
 assay at Oenococcus oeni
4.1.1.22 37
-
 assay at Lentilactobacillus hilgardii
4.1.1.22 37
-
 assay at Pediococcus parvulus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.22 4.8
-
 assay at Oenococcus oeni
4.1.1.22 4.8
-
 assay at Lentilactobacillus hilgardii
4.1.1.22 4.8
-
 assay at Pediococcus parvulus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Oenococcus oeni
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Lentilactobacillus hilgardii
4.1.1.22 pyridoxal 5'-phosphate activates, but does not influence the enzyme expression level Pediococcus parvulus