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Literature summary extracted from
- Evidence for an operative glyoxylate cycle in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius (2002), FEBS Lett., 513, 223-229.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | 3-nitropropionate | - |
Sulfolobus acidocaldarius |  |
| 4.1.3.1 | Itaconate | - |
Sulfolobus acidocaldarius | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.3.1 | 0.72 | - |
isocitrate | - |
Sulfolobus acidocaldarius | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | Mg2+ | dependent on Mg2+ | Sulfolobus acidocaldarius | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 46000 | - |
4 * 46000, SDS-PAGE | Sulfolobus acidocaldarius |
| 4.1.3.1 | 53750 | - |
4 * 53750, gel filtration | Sulfolobus acidocaldarius |
| 4.1.3.1 | 215000 | - |
gel filtration | Sulfolobus acidocaldarius |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.1 | Sulfolobus acidocaldarius | - |
strain DSM 639 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.3.1 | copurified with aconitase | Sulfolobus acidocaldarius |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 7.9 | - |
after 30fold purification | Sulfolobus acidocaldarius |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.1 | isocitrate | - |
Sulfolobus acidocaldarius | succinate + glyoxylate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | homotetramer | 4 * 46000, SDS-PAGE | Sulfolobus acidocaldarius |
| 4.1.3.1 | homotetramer | 4 * 53750, gel filtration | Sulfolobus acidocaldarius |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 80 | - |
- |
Sulfolobus acidocaldarius |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 6 | - |
- |
Sulfolobus acidocaldarius |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.3.1 | 0.015 | - |
3-nitropropionate | - |
Sulfolobus acidocaldarius | |
| 4.1.3.1 | 0.07 | - |
Itaconate | - |
Sulfolobus acidocaldarius | |
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Release 2023.1 (January 2023)
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