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Literature summary extracted from

  • Ulmer, W.; Froeschle, M.; Jany, K.D.
    Evidence for an essential histidine residue in glucose dehydrogenase from Bacillus megaterium and sequence analysis of the peptides labeled with bromoacetyl pyridine (1983), Eur. J. Biochem., 136, 183-194.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.47 3-(2-bromoacetyl)pyridine active-site-directed irreverseible inhibitor, the cofactor NAD but not the substrate glucose protects the enzyme from the inactivation, in the presence of 0.1 M NAD and 1.37 mM 3-(2-bromoacetyl)pyridine, glucose dehydrogenase has still 85% of its original activity after incubation for 2 h Priestia megaterium

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.47 Priestia megaterium P40288
-
-
1.1.1.47 Priestia megaterium IWG3 P40288
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.47 D-glucose + NAD(P)+
-
 Priestia megaterium D-glucono-1,5-lactone + NAD(P)H
-
 ?
1.1.1.47 D-glucose + NAD(P)+
-
 Priestia megaterium IWG3 D-glucono-1,5-lactone + NAD(P)H
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.47 glucose dehydrogenase
-
 Priestia megaterium

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.47 NAD+
-
 Priestia megaterium
1.1.1.47 NADP+
-
 Priestia megaterium

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.47 7.7
-
 3-(2-bromoacetyl)pyridine
-
 Priestia megaterium