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BRENDA support

Literature summary extracted from

  • Chicoine, J.; Benoit, P.; Gamberi, C.; Paliouras, M.; Simonelig, M.; Lasko, P.
    Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression (2007), Dev. Cell, 13, 691-704.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.13.4 additional information Bic-C activates CCR4-dependent deadenylation of specific mRNAs during early oogenesis. Bic-C binds specific segments of the Bic-C 50 untranslated region and negatively regulates its own expression by binding directly to NOT3/5, a component of the CCR4 core deadenylase complex. CCR4-HA and NOT3/5 form an RNase-resistant complex with Bic-C Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
3.1.13.4 Drosophila melanogaster
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.13.4 ovary
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Drosophila melanogaster
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Synonyms

EC Number Synonyms Comment Organism
3.1.13.4 CCR4 deadenylase complex
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Drosophila melanogaster