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Literature summary extracted from

  • Jennings, N.A.; Pezzementi, L.; Lawrence, A.L.; Watts, S.A.
    Acetylcholinesterase in the sea urchin Lytechinus variegatus: Characterization and developmental expression in larvae (2008), Comp. Biochem. Physiol. B, 149, 401-409.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 BW284c51
-
 Lytechinus variegatus
3.1.1.7 dichlorvos irreversible inhibition Lytechinus variegatus
3.1.1.7 ethopropazine
-
 Lytechinus variegatus
3.1.1.7 iso-ompa very poor inhibitor Lytechinus variegatus
3.1.1.7 neostigmine covalent, slow, and reversible inhibition Lytechinus variegatus
3.1.1.7 paraoxon irreversible inhibition Lytechinus variegatus
3.1.1.7 physostigmine covalent, slow, and reversible inhibition Lytechinus variegatus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.7 additional information
-
 additional information kinetics Lytechinus variegatus
3.1.1.7 0.036
-
 butyrylthiocholine
-
 Lytechinus variegatus
3.1.1.7 0.308
-
 acetylthiocholine
-
 Lytechinus variegatus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Lytechinus variegatus
-
 sea urchins collected from St. Joseph Bay, Florida in May of 2006
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 larva eight-arm F1 larvae Lytechinus variegatus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylthiocholine + H2O
-
 Lytechinus variegatus thiocholine + acetate
-
 ?
3.1.1.7 butyrylthiocholine + H2O
-
 Lytechinus variegatus thiocholine + butyrate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.7 dimer the enzyme exists in both dimeric and tetrameric globular forms Lytechinus variegatus
3.1.1.7 tetramer the enzyme exists in both dimeric and tetrameric globular forms Lytechinus variegatus

Synonyms

EC Number Synonyms Comment Organism
3.1.1.7 AChE
-
 Lytechinus variegatus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.7 22
-
 assay at room temperature Lytechinus variegatus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.7 7
-
 assay at Lytechinus variegatus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.7 additional information
-
 additional information inhibition kinetcis Lytechinus variegatus
3.1.1.7 0.000106
-
 physostigmine pH 7.0, 22°C Lytechinus variegatus
3.1.1.7 0.000718
-
 BW284c51 pH 7.0, 22°C Lytechinus variegatus
3.1.1.7 2.57
-
 ethopropazine pH 7.0, 22°C Lytechinus variegatus
3.1.1.7 30
-
 iso-ompa pH 7.0, 22°C Lytechinus variegatus