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Literature summary extracted from
- Tissue distribution and characterization of cholinesterase activity in six earthworm species (2007), Comp. Biochem. Physiol. B, 147B, 340-346.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.8 | BW284c51 | i.e. 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide, seletive inhibition of acetylthiocholine esterase activity | Aporrectodea caliginosa |  |
| 3.1.1.8 | BW284c51 | i.e. 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide, seletive inhibition of acetylthiocholine esterase activity | Aporrectodea nocturna | |
| 3.1.1.8 | BW284c51 | i.e. 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide, seletive inhibition of acetylthiocholine esterase activity | Aporrectodea rosea | |
| 3.1.1.8 | BW284c51 | i.e. 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide, seletive inhibition of acetylthiocholine esterase activity | Lumbricus castaneus | |
| 3.1.1.8 | BW284c51 | i.e. 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide, seletive inhibition of acetylthiocholine esterase activity | Lumbricus terrestris | |
| 3.1.1.8 | eserine | - |
Aporrectodea caliginosa | |
| 3.1.1.8 | eserine | - |
Aporrectodea nocturna | |
| 3.1.1.8 | eserine | - |
Aporrectodea rosea | |
| 3.1.1.8 | eserine | - |
Lumbricus castaneus | |
| 3.1.1.8 | eserine | - |
Lumbricus terrestris | |
| 3.1.1.8 | iso-ompa | i.e. tetra-(monoisopropyl)diphosphor-tetramide, selective inhibition of butyrylthiocholine esterase activity | Aporrectodea caliginosa | |
| 3.1.1.8 | iso-ompa | i.e. tetra-(monoisopropyl)diphosphor-tetramide, selective inhibition of butyrylthiocholine esterase activity | Aporrectodea nocturna | |
| 3.1.1.8 | iso-ompa | i.e. tetra-(monoisopropyl)diphosphor-tetramide, selective inhibition of butyrylthiocholine esterase activity | Aporrectodea rosea | |
| 3.1.1.8 | iso-ompa | i.e. tetra-(monoisopropyl)diphosphor-tetramide, selective inhibition of butyrylthiocholine esterase activity | Lumbricus castaneus | |
| 3.1.1.8 | iso-ompa | i.e. tetra-(monoisopropyl)diphosphor-tetramide, selective inhibition of butyrylthiocholine esterase activity | Lumbricus terrestris | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.8 | acetylthiocholine + H2O | Lumbricus terrestris | - |
thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | Lumbricus castaneus | - |
thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | Aporrectodea nocturna | - |
thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | Aporrectodea caliginosa | - |
thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | Aporrectodea rosea | - |
thiocholine + acetate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.8 | Aporrectodea caliginosa | - |
- |
- |
| 3.1.1.8 | Aporrectodea nocturna | - |
- |
- |
| 3.1.1.8 | Aporrectodea rosea | - |
- |
- |
| 3.1.1.8 | Lumbricus castaneus | - |
- |
- |
| 3.1.1.8 | Lumbricus terrestris | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.8 | crop | - |
Lumbricus terrestris | - |
| 3.1.1.8 | crop | - |
Lumbricus castaneus | - |
| 3.1.1.8 | crop | - |
Aporrectodea nocturna | - |
| 3.1.1.8 | crop | - |
Aporrectodea caliginosa | - |
| 3.1.1.8 | crop | - |
Aporrectodea rosea | - |
| 3.1.1.8 | gizzard | - |
Lumbricus terrestris | - |
| 3.1.1.8 | gizzard | - |
Lumbricus castaneus | - |
| 3.1.1.8 | gizzard | - |
Aporrectodea nocturna | - |
| 3.1.1.8 | gizzard | - |
Aporrectodea caliginosa | - |
| 3.1.1.8 | gizzard | - |
Aporrectodea rosea | - |
| 3.1.1.8 | nervous system | - |
Lumbricus terrestris | - |
| 3.1.1.8 | nervous system | - |
Lumbricus castaneus | - |
| 3.1.1.8 | nervous system | - |
Aporrectodea nocturna | - |
| 3.1.1.8 | nervous system | - |
Aporrectodea caliginosa | - |
| 3.1.1.8 | nervous system | - |
Aporrectodea rosea | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.8 | 0.092 | - |
crude whole body enzyme extract | Aporrectodea caliginosa |
| 3.1.1.8 | 0.096 | - |
crude whole body enzyme extract | Aporrectodea nocturna |
| 3.1.1.8 | 0.106 | - |
crude whole body enzyme extract | Aporrectodea rosea |
| 3.1.1.8 | 0.209 | - |
crude whole body enzyme extract | Lumbricus terrestris |
| 3.1.1.8 | 0.26 | - |
crude whole body enzyme extract | Lumbricus castaneus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.8 | acetylthiocholine + H2O | - |
Lumbricus terrestris | thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | - |
Lumbricus castaneus | thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | - |
Aporrectodea nocturna | thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | - |
Aporrectodea caliginosa | thiocholine + acetate | - |
? | |
| 3.1.1.8 | acetylthiocholine + H2O | - |
Aporrectodea rosea | thiocholine + acetate | - |
? | |
| 3.1.1.8 | butyrylthiocholine + H2O | - |
Lumbricus terrestris | thiocholine + butyrate | - |
? | |
| 3.1.1.8 | butyrylthiocholine + H2O | - |
Lumbricus castaneus | thiocholine + butyrate | - |
? | |
| 3.1.1.8 | butyrylthiocholine + H2O | - |
Aporrectodea nocturna | thiocholine + butyrate | - |
? | |
| 3.1.1.8 | butyrylthiocholine + H2O | - |
Aporrectodea caliginosa | thiocholine + butyrate | - |
? | |
| 3.1.1.8 | butyrylthiocholine + H2O | - |
Aporrectodea rosea | thiocholine + butyrate | - |
? | |
| 3.1.1.8 | additional information | tissue specificity of enzyme activities with different substrates, overview | Lumbricus terrestris | ? | - |
? | |
| 3.1.1.8 | additional information | tissue specificity of enzyme activities with different substrates, overview | Aporrectodea nocturna | ? | - |
? | |
| 3.1.1.8 | additional information | tissue specificity of enzyme activities with different substrates, overview | Aporrectodea caliginosa | ? | - |
? | |
| 3.1.1.8 | additional information | tissue specificity of enzyme activities with different substrates, overview | Aporrectodea rosea | ? | - |
? | |
| 3.1.1.8 | propionylthiocholine + H2O | - |
Lumbricus terrestris | thiocholine + propionate | - |
? | |
| 3.1.1.8 | propionylthiocholine + H2O | - |
Lumbricus castaneus | thiocholine + propionate | - |
? | |
| 3.1.1.8 | propionylthiocholine + H2O | - |
Aporrectodea nocturna | thiocholine + propionate | - |
? | |
| 3.1.1.8 | propionylthiocholine + H2O | - |
Aporrectodea caliginosa | thiocholine + propionate | - |
? | |
| 3.1.1.8 | propionylthiocholine + H2O | - |
Aporrectodea rosea | thiocholine + propionate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.1.8 | ChE | - |
Lumbricus terrestris |
| 3.1.1.8 | ChE | - |
Lumbricus castaneus |
| 3.1.1.8 | ChE | - |
Aporrectodea nocturna |
| 3.1.1.8 | ChE | - |
Aporrectodea caliginosa |
| 3.1.1.8 | ChE | - |
Aporrectodea rosea |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.8 | 20 | - |
assay at | Lumbricus terrestris |
| 3.1.1.8 | 20 | - |
assay at | Lumbricus castaneus |
| 3.1.1.8 | 20 | - |
assay at | Aporrectodea nocturna |
| 3.1.1.8 | 20 | - |
assay at | Aporrectodea caliginosa |
| 3.1.1.8 | 20 | - |
assay at | Aporrectodea rosea |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.8 | 7 | - |
assay at | Lumbricus terrestris |
| 3.1.1.8 | 7 | - |
assay at | Lumbricus castaneus |
| 3.1.1.8 | 7 | - |
assay at | Aporrectodea nocturna |
| 3.1.1.8 | 7 | - |
assay at | Aporrectodea caliginosa |
| 3.1.1.8 | 7 | - |
assay at | Aporrectodea rosea |
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