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Literature summary extracted from

  • Keidar, S.; Kaplan, M.; Gamliel-Lazarovich, A.
    ACE2 of the heart: From angiotensin I to angiotensin (1-7) (2007), Cardiovasc. Res., 73, 463-469.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.23 DX600
-
 Mus musculus
3.4.17.23 DX600
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.23 Mus musculus
-
-
-
3.4.17.23 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.23 heart
-
 Mus musculus
-
3.4.17.23 kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.23 angiotensin I + H2O
-
 Mus musculus angiotensin-(1-9) + Leu
-
 ?
3.4.17.23 angiotensin I + H2O
-
 Rattus norvegicus angiotensin-(1-9) + Leu
-
 ?
3.4.17.23 angiotensin II + H2O
-
 Mus musculus angiotensin-(1-7) + Phe
-
 ?
3.4.17.23 angiotensin II + H2O
-
 Rattus norvegicus angiotensin-(1-7) + Phe
-
 ?
3.4.17.23 apelin-13 + H2O high catalytic efficiency Mus musculus ?
-
 ?
3.4.17.23 apelin-13 + H2O high catalytic efficiency Rattus norvegicus ?
-
 ?
3.4.17.23 apelin-36 + H2O high catalytic efficiency Mus musculus ?
-
 ?
3.4.17.23 apelin-36 + H2O high catalytic efficiency Rattus norvegicus ?
-
 ?
3.4.17.23 beta-casomorphin + H2O
-
 Mus musculus ?
-
 ?
3.4.17.23 beta-casomorphin + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.23 des-Arg9-bradykinin + H2O
-
 Mus musculus ?
-
 ?
3.4.17.23 des-Arg9-bradykinin + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.23 dynorphin A + H2O
-
 Mus musculus ?
-
 ?
3.4.17.23 dynorphin A + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.23 Lys-des-Arg9-bradykinin + H2O
-
 Mus musculus ?
-
 ?
3.4.17.23 Lys-des-Arg9-bradykinin + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.17.23 additional information ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin Mus musculus ?
-
 ?
3.4.17.23 additional information ACE2 functions as a carboxymonopeptidase with a preference for C-terminal Leu or Phe, ACE2 counterbalances the enzymatic actions of ACE, ACE2 does not metabolize bradykinin Rattus norvegicus ?
-
 ?
3.4.17.23 neurotensin + H2O
-
 Mus musculus ?
-
 ?
3.4.17.23 neurotensin + H2O
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.23 ACE2
-
 Mus musculus
3.4.17.23 ACE2
-
 Rattus norvegicus