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Literature summary extracted from

  • Mohan, S.; Sim, L.; Rose, D.R.; Pinto, B.M.
    Synthesis of S-alkylated sulfonium-ions and their glucosidase inhibitory activities against recombinant human maltase glucoamylase (2007), Carbohydr. Res., 342, 901-912.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.3 1,4-dideoxy-1,4-[(1-butyl)-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[(1-hexyl)-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[(1-octadecyl)-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[(1-octyl)-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[(1-tetradecyl)-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[(1-tetradecyl)-(R)-episulfoniumylidene]-D-arabinitol triflate
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[[1-(3-methyl)-butyl]-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[[1-(6-ethoxy)-hexyl]-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1,4-dideoxy-1,4-[[1-(9-methoxy)-nonyl]-(R)-episulfoniumylidene]-D-arabinitol chloride
-
 Homo sapiens
3.2.1.3 1-deoxynojirimycin
-
 Homo sapiens
3.2.1.3 N-(7-oxadecyl)-1-deoxynojirimycin
-
 Homo sapiens
3.2.1.3 N-butyl-deoxynojirimycin
-
 Homo sapiens
3.2.1.3 N-decyl-deoxynojirimycin
-
 Homo sapiens
3.2.1.3 N-methyl-deoxynojirimycin
-
 Homo sapiens
3.2.1.3 salacinol
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.3 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.3 4-nitrophenyl alpha-D-glucopyranoside + H2O
-
 Homo sapiens 4-nitrophenol + D-glucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.3 maltase glucoamylase
-
 Homo sapiens
3.2.1.3 MGA
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.3 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.3 6.5
-
 assay at Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.2.1.3 0.00019
-
 salacinol pH 6.5, 37°C Homo sapiens
3.2.1.3 0.006
-
 1,4-dideoxy-1,4-[(1-tetradecyl)-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.01
-
 1,4-dideoxy-1,4-[(1-tetradecyl)-(R)-episulfoniumylidene]-D-arabinitol triflate pH 6.5, 37°C Homo sapiens
3.2.1.3 0.032
-
 1,4-dideoxy-1,4-[(1-butyl)-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.033
-
 1,4-dideoxy-1,4-[[1-(9-methoxy)-nonyl]-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.051
-
 1,4-dideoxy-1,4-[(1-octyl)-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.051
-
 1,4-dideoxy-1,4-[(1-octadecyl)-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.052
-
 1,4-dideoxy-1,4-[[1-(6-ethoxy)-hexyl]-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.067
-
 1,4-dideoxy-1,4-[[1-(3-methyl)-butyl]-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens
3.2.1.3 0.075
-
 1,4-dideoxy-1,4-[(1-hexyl)-(R)-episulfoniumylidene]-D-arabinitol chloride pH 6.5, 37°C Homo sapiens