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Literature summary extracted from

  • Chen, S.; Subbaiah, P.V.
    Phospholipid and fatty acid specificity of endothelial lipase: Potential role of the enzyme in the delivery of docosahexaenoic acid (DHA) to tissues (2007), Biochim. Biophys. Acta, 1771, 1319-1328.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.32 extracellular the enzyme is secreted by the cells of the blood-brain barrier Homo sapiens
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.32 additional information Homo sapiens the enzyme plays an important role in the metabolism of high density lipoproteins, it may be responsible for the generation of docosahexaenoic acid DHA lysophospholipids in plasma, DHA is important in brain development and neurological function, the endothelial lipase is important in the delivery of DHA lysophospholipid carriers to the brain, overview ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.32 Homo sapiens
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.32 brain the enzyme is secreted by the cells of the blood-brain barrier Homo sapiens
-
3.1.1.32 plasma
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 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.32 additional information substrate specificity, overview Homo sapiens ?
-
 ?
3.1.1.32 additional information the enzyme plays an important role in the metabolism of high density lipoproteins, it may be responsible for the generation of docosahexaenoic acid DHA lysophospholipids in plasma, DHA is important in brain development and neurological function, the endothelial lipase is important in the delivery of DHA lysophospholipid carriers to the brain, overview Homo sapiens ?
-
 ?
3.1.1.32 phosphatidylcholine + H2O phosphatidylcholine from shark liver Homo sapiens 2-acylglycerophosphocholine + a carboxylate
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 ?
3.1.1.32 phosphatidylethanolamine + H2O docosahexaenoic acid-enriched phosphatidylethanolamine vesicles Homo sapiens ?
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 ?
3.1.1.32 phosphatidylserine + H2O docosahexaenoic acid-enriched phosphatidylserine vesicles Homo sapiens ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.32 endothelial lipase
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 Homo sapiens