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Literature summary extracted from

  • Zhu, J.; Lu, C.; Standland, M.; Lai, E.; Moreno, G.N.; Umeda, A.; Jia, X.; Zhang, Z.
    Single mutation on the surface of Staphylococcus aureus sortase A can disrupt its dimerization (2008), Biochemistry, 47, 1667-1674.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.70 expression in Escherichia coli Staphylococcus aureus

Protein Variants

EC Number Protein Variants Comment Organism
3.4.22.70 I123G mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation reduces dimerization Staphylococcus aureus
3.4.22.70 K137A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation completely disrupts dimerization Staphylococcus aureus
3.4.22.70 K152A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation increases dimerization Staphylococcus aureus
3.4.22.70 K62A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template Staphylococcus aureus
3.4.22.70 N132A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation completely disrupts dimerization Staphylococcus aureus
3.4.22.70 P126G mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation reduces dimerization Staphylococcus aureus
3.4.22.70 Y143A mutant is generated by using wild type truncated protein SrtADELTAN59 as a template. Mutation completely disrupts dimerization Staphylococcus aureus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.70 Staphylococcus aureus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.70 of SrtADELTAN59 and mutant proteins Staphylococcus aureus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.70 Abz-LPETG-Dap(Dnp)-NH2 + GGGGG
-
 Staphylococcus aureus Abz-LPETGGGGGG + Gly-Dap(Dnp)-NH2
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.22.70 dimer
-
 Staphylococcus aureus

Synonyms

EC Number Synonyms Comment Organism
3.4.22.70 SrtA
-
 Staphylococcus aureus