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Literature summary extracted from

  • Chao, K.L.; Muthukumar, L.; Herzberg, O.
    Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis (2007), Biochemistry, 46, 6911-6920.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.35 expressed in Drosophila melanogaster Schneider 2 cells Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.2.1.35 hanging drop vapour diffusion method with mother liquor containing 1.5 M NaCl, 10% (v/v) ethanol, and 1/10 volume of 30% (w/v) galactose, at pH 4.6 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.35 47370
-
 calculated from sequence of cDNA Homo sapiens
3.2.1.35 50870
-
 MALDI-TOF mass spectrometry Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.35 Homo sapiens Q12794
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.35 glycoprotein
-
 Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.35 Chelating Sepharose Fast Flow column chromatography and Sephacryl S200 gel filtration Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.35 hyaluronan + 2 H2O
-
 Homo sapiens N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.35 endo-alpha-N-acetyl-hexosaminidase
-
 Homo sapiens
3.2.1.35 Hyal-1
-
 Homo sapiens
3.2.1.35 hyaluronidase-1
-
 Homo sapiens