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Literature summary extracted from

  • Yang, S.L.; Lou, Y.J.
    Sodium nitroprusside decreased leukotriene C4 generation by inhibiting leukotriene C4 synthase expression and activity in hepatic ischemia-reperfusion injured rats (2007), Biochem. Pharmacol., 73, 724-735.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.4.1.20 medicine sodium nitroprusside inhibits leukotriene C4 synthase activity and dwonregulates the protein expression of the enzyme Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.20 sodium nitroprusside in hepatic ischemia-reperfusion injured rats Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.20 Rattus norvegicus
-
 Sprague-Dawley
-
4.4.1.20 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.20 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.20 leukotriene A4 + glutathione
-
 Rattus norvegicus leukotriene C4
-
 ?
4.4.1.20 leukotriene A4 + glutathione
-
 Rattus norvegicus Sprague-Dawley leukotriene C4
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.20 leukotriene C4 synthetase
-
 Rattus norvegicus
4.4.1.20 LTC4 synthase
-
 Rattus norvegicus
4.4.1.20 LTC4S
-
 Rattus norvegicus