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Literature summary extracted from

  • Turner, D.J.; Pingle, M.R.; Barany, F.
    Harnessing asymmetrical substrate recognition by thermostable EndoV to achieve balanced linear amplification in multiplexed SNP typing (2006), Biochem. Cell Biol., 84, 232-242.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.21.7 additional information high pH, metal cofactor Mn2+, using excess enzyme, and/or solvents such as dimethyl sulfoxide and betaine, lead to cleavage of most mismatched DNA base pairs Thermotoga maritima

Application

EC Number Application Comment Organism
3.1.21.7 biotechnology method of linear amplification of DNA, allows 100fold amplification of target molecules Thermotoga maritima

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.7 Thermotoga maritima
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.7 DNA + H2O cleavage of unmodified duplex DNA Thermotoga maritima hydrolysed DNA
-
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Synonyms

EC Number Synonyms Comment Organism
3.1.21.7 endonuclease V
-
Thermotoga maritima
3.1.21.7 EndoV
-
Thermotoga maritima