EC Number | Application | Comment | Organism |
---|---|---|---|
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Bos taurus |
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Bacillus amyloliquefaciens |
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Kitasatospora aureofaciens |
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Aspergillus oryzae |
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Bacillus intermedius |
4.6.1.24 | medicine | RNase inhibitors appear to be promising for therapy of cancer | Penicillium brevicompactum |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.18 | chitosan | molecular weight about 6 kDA, complex formation with enzyme due to establishment of 5-6 ion pairs | Bos taurus | |
4.6.1.18 | additional information | not inhibitory: monoglucosamine up to 2 mM | Bos taurus | |
4.6.1.24 | chitosan | - |
Aspergillus oryzae | |
4.6.1.24 | chitosan | - |
Bacillus amyloliquefaciens | |
4.6.1.24 | chitosan | - |
Bacillus intermedius | |
4.6.1.24 | chitosan | - |
Bos taurus | |
4.6.1.24 | chitosan | - |
Kitasatospora aureofaciens | |
4.6.1.24 | chitosan | - |
Penicillium brevicompactum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.18 | Bos taurus | - |
Type XII A, commercial product, Sigma | - |
4.6.1.24 | Aspergillus oryzae | - |
- |
- |
4.6.1.24 | Bacillus amyloliquefaciens | - |
- |
- |
4.6.1.24 | Bacillus intermedius | - |
- |
- |
4.6.1.24 | Bos taurus | - |
- |
- |
4.6.1.24 | Kitasatospora aureofaciens | - |
- |
- |
4.6.1.24 | Penicillium brevicompactum | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.6.1.24 | - |
Bacillus amyloliquefaciens |
4.6.1.24 | - |
Kitasatospora aureofaciens |
4.6.1.24 | - |
Bacillus intermedius |
4.6.1.24 | - |
Penicillium brevicompactum |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.6.1.24 | pancreas | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.18 | poly(C) + H2O | - |
Bos taurus | 3'-CMP + 3'-phosphooligonucleotides | - |
? | |
4.6.1.18 | poly(I)poly(C) + H2O | - |
Bos taurus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.24 | barnase | - |
Bacillus amyloliquefaciens |
4.6.1.24 | Binase | - |
Bacillus intermedius |
4.6.1.24 | ribonuclease | - |
Bacillus amyloliquefaciens |
4.6.1.24 | ribonuclease | - |
Bacillus intermedius |
4.6.1.24 | ribonuclease A | - |
Bos taurus |
4.6.1.24 | ribonuclease Pb2 | - |
Penicillium brevicompactum |
4.6.1.24 | Ribonuclease SA | - |
Kitasatospora aureofaciens |
4.6.1.24 | ribonuclease T1 | - |
Aspergillus oryzae |
4.6.1.24 | RNase A | - |
Bos taurus |
4.6.1.24 | RNase Pb2 | - |
Penicillium brevicompactum |
4.6.1.24 | RNase Sa | - |
Kitasatospora aureofaciens |
4.6.1.24 | RNase T1 | - |
Aspergillus oryzae |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.6.1.18 | 0.00021 | - |
chitosan | substrate poly(I)poly(C), pH 7.0, 25°C | Bos taurus | |
4.6.1.18 | 0.00022 | - |
chitosan | substrate poly(C), pH 7.0, 25°C | Bos taurus | |
4.6.1.24 | 0.000033 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Kitasatospora aureofaciens | |
4.6.1.24 | 0.00008 | - |
chitosan | poly(A) * poly(U) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Penicillium brevicompactum | |
4.6.1.24 | 0.00009 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Penicillium brevicompactum | |
4.6.1.24 | 0.0001 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Bacillus intermedius | |
4.6.1.24 | 0.00012 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Bacillus amyloliquefaciens | |
4.6.1.24 | 0.00012 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Aspergillus oryzae | |
4.6.1.24 | 0.00021 | - |
chitosan | poly(I) * poly(C) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Bos taurus | |
4.6.1.24 | 0.00022 | - |
chitosan | poly(I) substrate, measurement is performed in 10 mM Tris, pH 7.0, containing 0.14 M NaCl and 0.1 mM EDTA | Bos taurus |