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Literature summary extracted from

  • Yang, H.C.; Yu, J.; Oh, K.B.; Shin, D.S.; Cho, W.J.; Shin, J.; Kim, S.
    Synthesis and evaluation of hydroquinone derivatives as inhibitors of isocitrate lyase (2007), Arch. Pharm. Res., 30, 955-961.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.3.1 (E)-2-(3-methylnon-2-enyl)benzene-1,4-diol
-
 Candida albicans
4.1.3.1 (E)-2-(4-hydroxy-3-methylbut-2-enyl)benzene-1,4-diol
-
 Candida albicans
4.1.3.1 (E)-2-(9-hydroxy-3-methylnon-2-enyl)benzene-1,4-diol
-
 Candida albicans
4.1.3.1 2-(3-methylbut-2-enyl)benzene-1,4-diol
-
 Candida albicans
4.1.3.1 2-allylbenzene-1,4-diol
-
 Candida albicans
4.1.3.1 halisulfate 1
-
 Candida albicans
4.1.3.1 halisulfate 5
-
 Candida albicans
4.1.3.1 hydrohalisulfate 1
-
 Candida albicans
4.1.3.1 Itaconate
-
 Candida albicans

Organism

EC Number Organism UniProt Comment Textmining
4.1.3.1 Candida albicans
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.3.1 isocitrate
-
 Candida albicans succinate + glyoxylate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.3.1 ICL
-
 Candida albicans

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
4.1.3.1 0.06
-
-
 Candida albicans Itaconate
4.1.3.1 0.28
-
-
 Candida albicans (E)-2-(9-hydroxy-3-methylnon-2-enyl)benzene-1,4-diol
4.1.3.1 0.29
-
-
 Candida albicans (E)-2-(4-hydroxy-3-methylbut-2-enyl)benzene-1,4-diol
4.1.3.1 0.4
-
-
 Candida albicans (E)-2-(3-methylnon-2-enyl)benzene-1,4-diol
4.1.3.1 0.61
-
-
 Candida albicans 2-(3-methylbut-2-enyl)benzene-1,4-diol
4.1.3.1 1.02
-
-
 Candida albicans 2-allylbenzene-1,4-diol