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Literature summary extracted from

  • Mattes, T.E.; Coleman, N.V.; Chuang, A.S.; Rogers, A.J.; Spain, J.C.; Gossett, J.M.
    Mechanism controlling the extended lag period associated with vinyl chloride starvation in Nocardioides sp. strain JS614 (2007), Arch. Microbiol., 187, 217-226.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.13.69 additional information epoxyethane, a metabolic intermediate of ethene biodegradation, induces enzyme expression, acetate reactivates extant AkMO in starved vinyl chloride- or ethene-grown cultures, overview Nocardioides sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.69 gene etnC, expression analysis under different culture conditions, overview Nocardioides sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.69 additional information inactivation of AkMO during starvation of cells Nocardioides sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.69 ethene + NADH + H+ + O2 Nocardioides sp.
-
 ?
-
 ?
1.14.13.69 ethene + NADH + H+ + O2 Nocardioides sp. JS614 / ATCC BAA-499
-
 ?
-
 ?
1.14.13.69 additional information Nocardioides sp. alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614 ?
-
 ?
1.14.13.69 additional information Nocardioides sp. JS614 / ATCC BAA-499 alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614 ?
-
 ?
1.14.13.69 vinyl chloride + NADH + H+ + O2 Nocardioides sp.
-
 ?
-
 ?
1.14.13.69 vinyl chloride + NADH + H+ + O2 Nocardioides sp. JS614 / ATCC BAA-499
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.69 Nocardioides sp.
-
 gene etnC
-
1.14.13.69 Nocardioides sp. JS614 / ATCC BAA-499
-
 gene etnC
-
4.4.1.23 Nocardioides sp. JS614
-
 40% of the initial enzyme activity remains after 24 h of carbon starvation, while alkene monooxygenase activity is lost after 7 h. This imbalance likely contributes to the extended lag period by delaying epoxide accumulation and subsequent alkene monooxygenase induction
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.69 culture condition:ethene-grown cell
-
 Nocardioides sp.
-
1.14.13.69 culture condition:vinyl chloride-grown cell
-
 Nocardioides sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.69 ethene + NADH + H+ + O2
-
 Nocardioides sp. ?
-
 ?
1.14.13.69 ethene + NADH + H+ + O2
-
 Nocardioides sp. JS614 / ATCC BAA-499 ?
-
 ?
1.14.13.69 additional information alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614 Nocardioides sp. ?
-
 ?
1.14.13.69 additional information alkene monooxygenase and epoxyalkane:coenzyme M transferase are the initial enzymes of vinyl chloride and ethene biodegradation in strain JS614 Nocardioides sp. JS614 / ATCC BAA-499 ?
-
 ?
1.14.13.69 vinyl chloride + NADH + H+ + O2
-
 Nocardioides sp. ?
-
 ?
1.14.13.69 vinyl chloride + NADH + H+ + O2
-
 Nocardioides sp. JS614 / ATCC BAA-499 ?
-
 ?
4.4.1.23 ethene + HS-CoM
-
 Nocardioides sp. JS614 ?
-
 ?
4.4.1.23 vinyl chloride + HS-CoM
-
 Nocardioides sp. JS614 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.69 AkMO
-
 Nocardioides sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.69 NADH
-
 Nocardioides sp.