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Literature summary extracted from

  • Soares, J.C.; Gabriel, D.; Folmer, V.; Augusti, G.R.; Rocha, J.B.
    High concentrations of glucose can activate or inhibit human erythrocyte aminolevulinate dehydratase in vitro depending exposure time (2006), Am. J. Biochem. Biotechnol., 2, 180-185.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.2.1.24 glucose incubations of erythrocytes for 24 h with glucose result in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.24 D-glucose incubations of erythrocytes for 24 h with glucose results in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.24 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.24 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.24 5-aminolevulinate + 5-aminolevulinate incubations of erythrocytes for 24 h with glucose result in an increase of delta-ALA-D activity. Incubations of erythrocytes with 100 to 200 mM glucose for 48 h inhibit delta-ALA-D activity Homo sapiens porphobilinogen + 2 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.24 delta-ALA-D
-
 Homo sapiens