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Literature summary extracted from

  • Bagautdinov, B.; Sugahara, M.; Kunishima, N.
    Purification, crystallization and preliminary crystallographic analysis of archaeal 6-pyruvoyl tetrahydrobiopterin synthase homologue PH0634 from Pyrococcus horikoshii OT3 (2007), Acta Crystallogr. Sect. F, 63, 15-17.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.2.3.12 overexpressed as native and selenomethionine-substituted protein and the purified protein is crystallized by the oil-microbatch method at 22°C. 2.1 A resolution from the native crystal using synchrotron radiation at 100 K. The crystal belongs to the orthorhombic space group P212121, with unit-cell parameters a = 35.83, b = 95.71, c = 05.65 A. The selenomethionine-substituted crystal is isomorphous to the native crystal and diffracts X-rays to 2.9 A Pyrococcus horikoshii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.12 6-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin Pyrococcus horikoshii the second of the three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.12 Pyrococcus horikoshii
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.3.12
-
 Pyrococcus horikoshii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.12 6-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin the second of the three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP Pyrococcus horikoshii ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.12 6-pyruvoyl tetrahydrobiopterin synthase
-
 Pyrococcus horikoshii
4.2.3.12 PH0634
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 Pyrococcus horikoshii