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Literature summary extracted from

  • Ewan, L.C.; Jopling, H.M.; Jia, H.; Mittar, S.; Bagherzadeh, A.; Howell, G.J.; Walker, J.H.; Zachary, I.C.; Ponnambalam, S.
    Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells (2006), Traffic, 7, 1270-1282.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 SU5416 selective inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine Homo sapiens
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 endothelial cell
-
 Homo sapiens
-
2.7.10.1 HEK-293T cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 Flk-1
-
 Homo sapiens
2.7.10.1 KDR/fetal liver kinase-1
-
 Homo sapiens
2.7.10.1 vascular endothelial growth factor receptor 2
-
 Homo sapiens
2.7.10.1 VEGFR2/kinase domain region
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.1 ATP
-
 Homo sapiens