EC Number | Cloned (Comment) | Organism |
---|---|---|
6.1.1.21 | DNA and amino acid sequence determination and analysis of HisRS gene variants, HisRS genes, which map closely to the Egr1 locus, have conserved the 129/Sv haplotype despite numerous back-crossing of the null mice progeny with C57Bl/6J animals, genetic analysis of isozymes of HisRS encoded by the 129/Sv haplotype, allelic difference for mortalin and HisRS between 129/Sv and C57Bl/6J strains, overview | Mus musculus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
6.1.1.21 | additional information | construction of Egr1 null or defect mutants affects HisRS genes, Egr1, Zif268, is an immediate early gene encoding an inducible transcription factor involved in synaptic plasticity and several forms of memory in rodents, allelic differences between mouse strains can introduce variations in differential proteomic analyses of genetically modified organisms | Mus musculus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.21 | Mg2+ | - |
Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.21 | ATP + L-histidine + tRNAHis | Mus musculus | - |
AMP + diphosphate + L-histidinyl-tRNAHis | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.21 | Mus musculus | - |
Egr1 genetically modified mice, several isozymes through allelic difference of HisRS between 129/Sv and C57Bl/6J strains | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.21 | ATP + L-histidine + tRNAHis | - |
Mus musculus | AMP + diphosphate + L-histidinyl-tRNAHis | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.21 | HisRS | - |
Mus musculus |
6.1.1.21 | histidyl-transfer RNA synthetase | - |
Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.21 | ATP | - |
Mus musculus |