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Literature summary extracted from

  • Selvakumar, P.; Lakshmikuttyamma, A.; Shrivastav, A.; Das, S.B.; Dimmock, J.R.; Sharma, R.K.
    Potential role of N-myristoyltransferase in cancer (2007), Prog. Lipid Res., 46, 1-36.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.97
-
 Bos taurus
2.3.1.97 expression in Escherichia coli Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.97 1,12-dodecanedicarboxylic acid IC50 above 100 mM Homo sapiens
2.3.1.97 1,3-dimyristoylglycerol IC50 above 100 mM Homo sapiens
2.3.1.97 1-myristoyl-rac-glycerol IC50 in the range 1-100 mM Homo sapiens
2.3.1.97 1-Tetradecanal IC50 in the range 1-100 mM Homo sapiens
2.3.1.97 1-Tetradecanol IC50 above 100 mM Homo sapiens
2.3.1.97 2-dodecylglycidoyl-S-CoA IC50 below 1 mM Homo sapiens
2.3.1.97 3-tetradecyn-1-ol IC50 above 100 mM Homo sapiens
2.3.1.97 enolase
-
 Homo sapiens
2.3.1.97 lauric acid IC50 below 1 mM Homo sapiens
2.3.1.97 myristelaidic acid IC50 below 1 mM Homo sapiens
2.3.1.97 myristic acid IC50 in the range 1-100 mM Homo sapiens
2.3.1.97 myristoleic acid IC50 below 1 mM Homo sapiens
2.3.1.97 N(2-S-CoA-tetradecanoyl)glycinamide IC50 below 1 mM Homo sapiens
2.3.1.97 palmitic acid IC50 in the range 1-100 mM Homo sapiens
2.3.1.97 S-(2-bromotetradecanoyl)-CoA IC50 below 1 mM Homo sapiens
2.3.1.97 S-(2-ketopentadecyl)-CoA IC50: 0.00006 mM Homo sapiens
2.3.1.97 tetradecyl trimethylammonium bromide IC50 above 100 mM Homo sapiens
2.3.1.97 tetradecyl triphenylphosphonium bromide IC50 above 100 mM Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.97 additional information
-
 additional information
-
 Oryctolagus cuniculus
2.3.1.97 additional information
-
 additional information
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.97 cytosol
-
 Homo sapiens 5829
-
2.3.1.97 cytosol
-
 Saccharomyces cerevisiae 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.97 Bos taurus P31717
-
-
2.3.1.97 Bos taurus Q9N181
-
-
2.3.1.97 Homo sapiens O60551
-
-
2.3.1.97 Homo sapiens P30419
-
-
2.3.1.97 Oryctolagus cuniculus
-
-
-
2.3.1.97 Rattus norvegicus Q8K1Q0
-
-
2.3.1.97 Saccharomyces cerevisiae P14743
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.97 colonic mucosa
-
 Oryctolagus cuniculus
-
2.3.1.97 liver
-
 Homo sapiens
-
2.3.1.97 liver
-
 Rattus norvegicus
-
2.3.1.97 spleen
-
 Homo sapiens
-
2.3.1.97 spleen
-
 Bos taurus
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.97 cell division control protein 72
-
 Saccharomyces cerevisiae
2.3.1.97 dipeptide N-myristoyltransferase 2
-
 Bos taurus
2.3.1.97 glycylpeptide N-tetradecanoyltransferase
-
 Saccharomyces cerevisiae
2.3.1.97 glycylpeptide N-tetradecanoyltransferase 1
-
 Bos taurus
2.3.1.97 glycylpeptide N-tetradecanoyltransferase 1
-
 Rattus norvegicus
2.3.1.97 glycylpeptide N-tetradecanoyltransferase 2
-
 Homo sapiens
2.3.1.97 glycylpeptide N-tetradecanoyltransferase 2
-
 Bos taurus
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase
-
 Saccharomyces cerevisiae
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase 1
-
 Homo sapiens
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase 1
-
 Bos taurus
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase 1
-
 Rattus norvegicus
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase 2
-
 Homo sapiens
2.3.1.97 myristoyl-CoA:protein N-myristoyltransferase 2
-
 Bos taurus
2.3.1.97 myristoyltransferase
-
 Oryctolagus cuniculus
2.3.1.97 myristoyltransferase
-
 Homo sapiens
2.3.1.97 myristoyltransferase
-
 Bos taurus
2.3.1.97 myristoyltransferase
-
 Rattus norvegicus
2.3.1.97 myristoyltransferase
-
 Saccharomyces cerevisiae
2.3.1.97 NMT
-
 Saccharomyces cerevisiae
2.3.1.97 NMT 1
-
 Homo sapiens
2.3.1.97 NMT 1
-
 Bos taurus
2.3.1.97 NMT 1
-
 Rattus norvegicus
2.3.1.97 NMT 2
-
 Homo sapiens
2.3.1.97 NMT 2
-
 Bos taurus
2.3.1.97 peptide N-myristoyltransferase
-
 Saccharomyces cerevisiae
2.3.1.97 peptide N-myristoyltransferase 1
-
 Homo sapiens
2.3.1.97 peptide N-myristoyltransferase 1
-
 Bos taurus
2.3.1.97 peptide N-myristoyltransferase 1
-
 Rattus norvegicus
2.3.1.97 peptide N-myristoyltransferase 2
-
 Homo sapiens
2.3.1.97 type I N-myristoyltransferase
-
 Homo sapiens
2.3.1.97 type I N-myristoyltransferase
-
 Bos taurus
2.3.1.97 type I N-myristoyltransferase
-
 Rattus norvegicus
2.3.1.97 type II N-myristoyltransferase
-
 Homo sapiens
2.3.1.97 type II N-myristoyltransferase
-
 Bos taurus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.3.1.97 0.00006
-
 IC50: 0.00006 mM Homo sapiens S-(2-ketopentadecyl)-CoA
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens lauric acid
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens myristoleic acid
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens myristelaidic acid
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens S-(2-bromotetradecanoyl)-CoA
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens N(2-S-CoA-tetradecanoyl)glycinamide
2.3.1.97 1
-
 IC50 below 1 mM Homo sapiens 2-dodecylglycidoyl-S-CoA
2.3.1.97 1 100 IC50 in the range 1-100 mM Homo sapiens palmitic acid
2.3.1.97 1 100 IC50 in the range 1-100 mM Homo sapiens myristic acid
2.3.1.97 1 100 IC50 in the range 1-100 mM Homo sapiens 1-Tetradecanal
2.3.1.97 1 100 IC50 in the range 1-100 mM Homo sapiens 1-myristoyl-rac-glycerol
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens 1-Tetradecanol
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens tetradecyl trimethylammonium bromide
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens 3-tetradecyn-1-ol
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens 1,12-dodecanedicarboxylic acid
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens 1,3-dimyristoylglycerol
2.3.1.97 100
-
 IC50 above 100 mM Homo sapiens tetradecyl triphenylphosphonium bromide