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Literature summary extracted from

  • Zhang, X.; Reddy, S.Y.; Bruice, T.C.
    Mechanism of methanol oxidation by quinoprotein methanol dehydrogenase (2007), Proc. Natl. Acad. Sci. USA, 104, 745-749.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.2.7 Ca2+ required Methylophilus methylotrophus

Organism

EC Number Organism UniProt Comment Textmining
1.1.2.7 Methylophilus methylotrophus P38539 and P38540 P38539 (large subunit, alpha) and P38540 (small subunit, beta)
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.2.7 a primary alcohol + 2 ferricytochrome cL = an aldehyde + 2 ferrocytochrome cL + 2 H+ detailed mechanism of methanol oxidation involving residues Asp297 and Glu171, structure-activity analysis by quantum mechanics and molecular mechanics, QM/MM, selfconsistent-charge density-functional tight-binding, SCC-DFTB, and molecular dynamics, the transition state involves Glu171-CO2- as general base Methylophilus methylotrophus
a

Synonyms

EC Number Synonyms Comment Organism
1.1.2.7 MDH
-
 Methylophilus methylotrophus
1.1.2.7 quinoprotein methanol dehydrogenase
-
 Methylophilus methylotrophus
1.1.5.5 MDH
-
-
1.1.5.5 quinoprotein methanol dehydrogenase
-
-

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.2.7 pyrroloquinoline quinone
-
 Methylophilus methylotrophus