Any feedback?
Literature summary extracted from
- Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydro-isoquinoline alkaloids (2005), Pol. J. Pharmacol., 56, 727-734.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.16.2 | 1,2,3,4-tetrahydropapaveroline | 50% inhibition at 7.5 microM | Rattus norvegicus |  |
| 1.14.16.2 | salsolinol | 50% inhibition at 35.4 microM and 4.1 microM when assayed at 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine concentration of 0.5 mM or 0.25 mM, respectively | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.16.2 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.16.2 | corpus striatum | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.16.2 | L-tyrosine + 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine + O2 | - |
Rattus norvegicus | 3,4-dihydroxyphenylalanine + ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.16.2 | TH | - |
Rattus norvegicus |
| 1.14.16.2 | tyrosine hydroxylase | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
