EC Number | Application | Comment | Organism |
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2.7.1.145 | medicine | deoxynucleoside kinase gene is introduced into HeLa cells with cationic lipids, to allow its transient expression. Cytotoxicities of 1-beta-D-arabinofuranosylcytosine, 5-fluorodeoxyuridine, and 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytosine are increased by the deoxynucleoside kinase gene. The combination of the transient expression of the Drosophila deoxynucleoside kinase gene and these nucleoside analogs is a candidate for suicide gene therapy | Drosophila melanogaster |
EC Number | Cloned (Comment) | Organism |
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2.7.1.145 | deoxynucleoside kinase gene is introduced into HeLa cells with cationic lipids, to allow its transient expression. Cytotoxicities of 1-beta-D-arabinofuranosylcytosine, 5-fluorodeoxyuridine, and 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytosine are increased by the deoxynucleoside kinase gene. The combination of the transient expression of the Drosophila deoxynucleoside kinase gene and these nucleoside analogs is a candidate for suicide gene therapy | Drosophila melanogaster |
EC Number | Organism | UniProt | Comment | Textmining |
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2.7.1.145 | Drosophila melanogaster | - |
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EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
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2.7.1.145 | additional information | transient expression of Drosophila melanogaster deoxynucleoside kinase gene in HeLa cells enhances cytotoxicity of nucleoside analogs | Drosophila melanogaster | ? | - |
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