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Literature summary extracted from

  • Tapinos, N.; Ohnishi, M.; Rambukkana, A.
    ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli (2006), Nat. Med., 12, 961-966.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 herceptin
-
 Homo sapiens
2.7.10.1 herceptin
-
 Mus musculus
2.7.10.1 herceptin
-
 Rattus norvegicus
2.7.10.1 PKI-166
-
 Homo sapiens
2.7.10.1 PKI-166
-
 Mus musculus
2.7.10.1 PKI-166 0.5 mM/kg body weight Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.10.1 120000
-
 SDS-PAGE Mus musculus
2.7.10.1 120000
-
 SDS-PAGE Homo sapiens
2.7.10.1 120000
-
 SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine Mus musculus
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine Homo sapiens
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine Rattus norvegicus
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Homo sapiens
-
-
-
2.7.10.1 Mus musculus
-
-
-
2.7.10.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 Schwann cell
-
 Mus musculus
-
2.7.10.1 Schwann cell
-
 Homo sapiens
-
2.7.10.1 Schwann cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Mus musculus ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Rattus norvegicus ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 erbB2 receptor tyrosine kinase
-
 Mus musculus
2.7.10.1 erbB2 receptor tyrosine kinase
-
 Homo sapiens
2.7.10.1 erbB2 receptor tyrosine kinase
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.1 ATP
-
 Mus musculus
2.7.10.1 ATP
-
 Homo sapiens
2.7.10.1 ATP
-
 Rattus norvegicus