EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Haloferax volcanii | ATP-dependent DNA ligase LigA is non-essential for cell viability. Haloferax volcanii also encodes the NAD+-dependent DNA ligase LigN. As with LigA, LigN is also non-essential for cell viability. Simultaneous inactivation of both proteins is lethal, however, indicating that they share an essential function | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.2 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Haloferax volcanii | NAD+-dependent DNA ligase LigN is non-essential for cell viability. Haloferax volcanii also encodes the ATP-dependent DNA ligase LigA. As with LigN, LigA is also non-essential for cell viability. Simultaneous inactivation of both proteins is lethal, however, indicating that they share an essential function | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.5.1.1 | Haloferax volcanii | - |
- |
- |
6.5.1.2 | Haloferax volcanii | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | ATP-dependent DNA ligase LigA is non-essential for cell viability. Haloferax volcanii also encodes the NAD+-dependent DNA ligase LigN. As with LigA, LigN is also non-essential for cell viability. Simultaneous inactivation of both proteins is lethal, however, indicating that they share an essential function | Haloferax volcanii | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
6.5.1.2 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | NAD+-dependent DNA ligase LigN is non-essential for cell viability. Haloferax volcanii also encodes the ATP-dependent DNA ligase LigA. As with LigN, LigA is also non-essential for cell viability. Simultaneous inactivation of both proteins is lethal, however, indicating that they share an essential function | Haloferax volcanii | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.5.1.1 | ATP-dependent DNA ligase | - |
Haloferax volcanii |
6.5.1.1 | LigA | - |
Haloferax volcanii |
6.5.1.2 | LigN | - |
Haloferax volcanii |
6.5.1.2 | NAD+-dependent DNA ligase | - |
Haloferax volcanii |