Literature summary extracted from

Peltier, S.; Burelle, Y.; Novel-Chate, V.; Demaison, L.; Verdys, M.; Saks, V.; Keriel, C.; Leverve, X.M.
Effect of exogenous adenosine and monensin on glycolytic flux in isolated perfused normoxic rat hearts: role of pyruvate kinase (2005), Mol. Cell. Biochem., 277, 55-61.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.1.40	Myxothiazol	0.0001 mM	Rattus norvegicus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.40	adenosine	0.01 mM	Rattus norvegicus
2.7.1.40	hexanoate	0.5 mM	Rattus norvegicus
2.7.1.40	MgATP2-	potent inhibitor	Rattus norvegicus
2.7.1.40	monensin	0.0005 mM	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.40	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.40	heart	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.40	ADP + phosphoenolpyruvate	-	Rattus norvegicus	ATP + pyruvate	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.1.40	ADP	-	Rattus norvegicus

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Release 2023.1 (January 2023)