Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Canter, J.A.; Summar, M.L.; Smith, H.B.; Rice, G.D.; Hall, L.D.; Ritchie, M.D.; Motsinger, A.A.; Christian, K.G.; Drinkwater, D.C.; Scholl, F.G.; Dyer, K.L.; Kavanaugh-McHugh, A.L.; Barr, F.E.
    Genetic variation in the mitochondrial enzyme carbamyl-phosphate synthetase I predisposes children to increased pulmonary artery pressure following surgical repair of congenital heart defects: a validated genetic association study (2007), Mitochondrion, 7, 204-210.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.3.4.16 N-acetylglutamate essential Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
6.3.4.16 T1405N significant change in CPSI enzymatic function Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.4.16 mitochondrion
-
 Homo sapiens 5739
-

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.16 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.16 blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.16 ATP + NH4+ + CO2 + H2O
-
 Homo sapiens ADP + phosphate + carbamoylphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.16 carbamyl-phosphate synthetase I
-
 Homo sapiens
6.3.4.16 CPSI
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.4.16 ATP
-
 Homo sapiens