Literature summary extracted from

Aktas, E.; Durmaz, R.; Yang, D.; Yang, Z.
Molecular characterization of isoniazid and rifampin resistance of Mycobacterium tuberculosis clinical isolates from Malatya, Turkey (2005), Microb. Drug Resist., 11, 94-99.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.11.1.6	S315T	mutation at katG codon 315 detected in 17 (63.0%) of the 27 isoniazid-resistant isolates analyzed. The most prevalent mutation observed is AGC315ACC (Ser315Thr), involving 11(65%) of the 17 isoniazid-resistant isolates having a mutation in the sequenced region. Ten isoniazid-resistant and all 29 isoniazid-susceptible isolates sequenced have no mutation in this region. Of the 19 multi-drug-resistant isolates, 15 (78.9%) show a mutation in codon 315, while only two (25%) of the eight isoniazid mono-resistant isolates are found to have a mutation in that codon	Mycobacterium tuberculosis

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.11.1.6	Mycobacterium tuberculosis	-	clinical isolates from Malatya, Turkey	-

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Release 2023.1 (January 2023)