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Literature summary extracted from

  • Shonsey, E.M.; Sfakianos, M.; Johnson, M.; He, D.; Falany, C.N.; Falany, J.; Merkler, D.J.; Barnes, S.
    Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids (2005), Methods Enzymol., 400, 374-394.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.65 expression in Escherichia coli Homo sapiens
2.3.1.65 expression in Sf9 cells Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.65 1
-
taurine 37°C, pH 8.4 Homo sapiens
2.3.1.65 2
-
aminomethanesulfonic acid 37°C, pH 8.4 Homo sapiens
2.3.1.65 2
-
2-fluoro-beta-alanine 37°C, pH 8.4 Homo sapiens
2.3.1.65 5
-
glycine 37°C, pH 8.4 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.65 Homo sapiens Q14032
-
-
2.3.1.65 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.65
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.65 liver
-
Rattus norvegicus
-
2.3.1.65 liver
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.65 0.0635
-
activity measured with taurine as substrate Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.65 choloyl-CoA + 2-fluoro-beta-alanine
-
Homo sapiens ?
-
?
2.3.1.65 choloyl-CoA + aminomethanesulfonic acid
-
Homo sapiens ?
-
?
2.3.1.65 choloyl-CoA + glycine
-
Homo sapiens CoA + glycocholate
-
?
2.3.1.65 choloyl-CoA + taurine
-
Homo sapiens CoA + taurocholate
-
?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.65 bile acid coenzyme A: amino acid N-acyltransferase
-
Rattus norvegicus
2.3.1.65 bile acid coenzyme A:amino acid N-acyltransferase
-
Homo sapiens
2.3.1.65 hBAT
-
Homo sapiens
2.3.1.65 rBAT
-
Rattus norvegicus