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Literature summary extracted from

  • Bian, H.S.; Ngo, S.Y.; Tan, W.; Wong, C.H.; Boelsterli, U.A.; Tan, T.M.
    Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids (2007), Life Sci., 81, 1659-1667.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.8.2.1 additional information glucocorticoids and prednisolone induce SULT1A3 activity on dopamine 1.2-1.8fold, but not SULT1A1, no effect by dexamethasone in Hep-G2 cells on SULT1A3 activity on 4-nitrophenol Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.1 SULT1A3 and SULT1A1, expression analysis in Hep-G2 cells in response to glucocorticoids prednisolone and dexamethasone Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.1 additional information no effect by dexamethasone in Hep-G2 cells on SULT1A3 activity on 4-nitrophennol Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + 4-nitrophenol Homo sapiens
-
 adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylyl sulfate + dopamine Homo sapiens
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 additional information Homo sapiens regulation of human SULT1A genes by glucocorticoids, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Homo sapiens P0DMM9
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.1 Hep-G2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + 4-nitrophenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylyl sulfate + dopamine
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 additional information regulation of human SULT1A genes by glucocorticoids, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.1 sulfotransferase 1A3
-
 Homo sapiens
2.8.2.1 SULT1A3
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.1 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.1 6.5
-
 assay at Homo sapiens