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Literature summary extracted from

  • Carneiro de Lyra, E.; Amorim da Silva, I.; Katayama, M.L.; Brentani, M.M.; Nonogaki, S.; Goes, J.C.; Folgueira, M.A.
    25(OH)D3 and 1,25(OH)2D3 serum concentration and breast tissue expression of 1alpha-hydroxylase, 24-hydroxylase and Vitamin D receptor in women with and without breast cancer (2006), J. Steroid Biochem. Mol. Biol., 100, 184-192.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D + NADPH + O2 Homo sapiens 1,25(OH)2D3 is an antiproliferative agent that may inhibit proliferation of breast cancer cells 1alpha,25-dihydroxyvitamin D + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.18 Homo sapiens
-
 women with and without breast cancer
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.18 breast enzyme expression analysis in different samples of women with and without breast cancer, no correlation with breast cancer development Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D + NADPH + O2
-
 Homo sapiens 1alpha,25-dihydroxyvitamin D + NADP+ + H2O
-
 ?
1.14.15.18 25-hydroxyvitamin D + NADPH + O2 1,25(OH)2D3 is an antiproliferative agent that may inhibit proliferation of breast cancer cells Homo sapiens 1alpha,25-dihydroxyvitamin D + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.15.18 1alpha-hydroxylase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.15.18 NADPH
-
 Homo sapiens