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Literature summary extracted from

  • Scholten, A.; van Veen, T.A.; Vos, M.A.; Heck, A.J.
    Diversity of cAMP-dependent protein kinase isoforms and their anchoring proteins in mouse ventricular tissue (2007), J. Proteome Res., 6, 1705-1717.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.11 cAMP
-
 Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.11 recombinant expression of paralemmin 2-AKAP2 fusion protein in ventricular tissue Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.11 additional information individually phosphorylated PKA-R isozymes are differentially targeted to distinct cellular compartments by AKAP-isozymes Mus musculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.11 Mg2+
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.11 additional information Mus musculus the enzyme is involved in cyclic nucleotide signaling, overview, individually phosphorylated PKA-R isozymes are differentially targeted to distinct cellular compartments by AKAP-isozymes, providing a multifaceted platform for the kinase ?
-
 ?
2.7.11.11 additional information Mus musculus FVB/N the enzyme is involved in cyclic nucleotide signaling, overview, individually phosphorylated PKA-R isozymes are differentially targeted to distinct cellular compartments by AKAP-isozymes, providing a multifaceted platform for the kinase ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.11 Mus musculus
-
 FVB/N mice
-
2.7.11.11 Mus musculus FVB/N
-
 FVB/N mice
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.11 phosphoprotein analysis of in vivo phosphorylation sites on PKA-R reveals the presence of several differentially phosphorylated PKA-R isoforms, using semiquantitative mass spectrometry, overview Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.11 heart
-
 Mus musculus
-
2.7.11.11 heart ventricle isozyme distribution Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.11 additional information the enzyme is involved in cyclic nucleotide signaling, overview, individually phosphorylated PKA-R isozymes are differentially targeted to distinct cellular compartments by AKAP-isozymes, providing a multifaceted platform for the kinase Mus musculus ?
-
 ?
2.7.11.11 additional information the enzyme is involved in cyclic nucleotide signaling, overview, individually phosphorylated PKA-R isozymes are differentially targeted to distinct cellular compartments by AKAP-isozymes, providing a multifaceted platform for the kinase Mus musculus FVB/N ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.11 More identification of protein kinase A regulatory isoforms and of 11 different A-kinase anchoring proteins, AKAPs, in ventricular tissue, overview Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.7.11.11 PKA
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.11 ATP
-
 Mus musculus