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Literature summary extracted from

  • Bharatham, N.; Bharatham, K.; Lee, K.W.
    Pharmacophore identification and virtual screening for methionyl-tRNA synthetase inhibitors (2007), J. Mol. Graph. Model., 25, 813-823.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.10 additional information inhibitor screening, hstructures, omology modeling, molecular docking studies, and computational development of pharmacophore models, overview; inhibitor screening, structures, homology modeling, molecular docking studies, and computational development of pharmacophore models, overview Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.10 Mg2+
-
 Staphylococcus aureus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.10 ATP + L-methionine + tRNAMet Staphylococcus aureus
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.10 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.10 ATP + L-methionine + tRNAMet
-
 Staphylococcus aureus AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Subunits

EC Number Subunits Comment Organism
6.1.1.10 More three-dimensional structure of MetRS by homology modeling method, overview Staphylococcus aureus

Synonyms

EC Number Synonyms Comment Organism
6.1.1.10 methionyl-tRNA synthetase
-
 Staphylococcus aureus
6.1.1.10 MetRS
-
 Staphylococcus aureus

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.10 ATP
-
 Staphylococcus aureus