EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.1.60 | expressed in Sf-9 cells | Rattus norvegicus |
5.1.3.14 | expression in insect cells | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.1.3.14 | CMP-Neu5Ac | allosterical feed-back-inhibition | Rattus norvegicus | |
5.1.3.14 | UDP | competitive inhibition | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.60 | cytosol | - |
Rattus norvegicus | 5829 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.60 | 83500 | - |
4 * 83500, dynamic light scattering, the tetramer likely represents the active state of the enzyme in the cell | Rattus norvegicus |
2.7.1.60 | 85000 | - |
4 * 85000, gel filtration | Rattus norvegicus |
2.7.1.60 | 334000 | - |
dynamic light scattering | Rattus norvegicus |
2.7.1.60 | 340000 | - |
gel filtration | Rattus norvegicus |
5.1.3.14 | 330000 | - |
dynamic light-scattering | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.3.14 | UDP-GlcNAc + H2O | Rattus norvegicus | biosynthesis of sialic acids | ManNAc + UDP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.60 | Rattus norvegicus | - |
- |
- |
5.1.3.14 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.60 | MonoQ HR 5/5 column chromatography, PD-10 column chromatography, and Superdex 200 gel filtration | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.60 | liver | - |
Rattus norvegicus | - |
5.1.3.14 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.60 | ATP + N-acetyl-D-mannosamine | - |
Rattus norvegicus | ADP + N-acetyl-D-mannosamine 6-phosphate | - |
? | |
5.1.3.14 | UDP-GlcNAc + H2O | biosynthesis of sialic acids | Rattus norvegicus | ManNAc + UDP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.60 | tetramer | 4 * 83500, dynamic light scattering, the tetramer likely represents the active state of the enzyme in the cell | Rattus norvegicus |
2.7.1.60 | tetramer | 4 * 85000, gel filtration | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.60 | GNE | - |
Rattus norvegicus |
2.7.1.60 | UDP-GlcNAc-epimerase/ManNAc kinase | - |
Rattus norvegicus |
2.7.1.60 | UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | - |
Rattus norvegicus |
5.1.3.14 | His-rGNE | - |
Rattus norvegicus |
5.1.3.14 | UDP-N-acetylglucosamine 2-epimerase | - |
Rattus norvegicus |