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Literature summary extracted from

  • Weihofen, W.A.; Berger, M.; Chen, H.; Saenger, W.; Hinderlich, S.
    Structures of human N-acetylglucosamine kinase in two complexes with N-acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation (2006), J. Mol. Biol., 364, 388-399.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.59 expressed in Escherichia coli strain BL21 (DE3) Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.1.59 in 100 mM HEPES (pH 7.0), 100 mM NaCl, 8% (w/v) PEG 4000 and 2 mM N-acetyl-D-glucosamine Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.59 Homo sapiens Q9UJ70
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.59 glutathione Sepharose column chromatography, MonoQ HR 5/5 column chromatography, and Superdex75 gel filtration Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.59 ATP + N-acetyl-D-glucosamine
-
 Homo sapiens ADP + N-acetyl-D-glucosamine 6-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.59 homodimer x-ray crystallography Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.1.59 GlcNAc kinase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.59 ATP
-
 Homo sapiens